After more than 50 years as a writer, Roth decided that 2010?s ?Nemesis,? the story of a polio epidemic in the Newark, New Jersey, neighborhood where he grew up, would be his last novel.Roth?s best-known work was the 1969 novel ?Portnoy?s Complaint,? a first-person narrative about Alexander Portnoy, a young middle-class Jewish New Yorker.

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